Progressive Supranuclear Palsy: A Case Report and Literature Review

Author(s): Samar Ikram, Valeria D. Parra-Payano, Thirumala Keerthi Chandrika Kammaripalle, Abhigyan Datta, Manpreet Kaur, Tanushri Bhushan, Marlliny Sullivan, Abeer Mastoor, Humza Haroon, Ali Guy, Masum Rahma

Progressive supranuclear palsy (PSP) is a rare neurodegenerative disease with a prevalence of five to six persons per 100,000 people and characterized by progressive axial rigidity, vertical supranuclear gaze palsy, frontal lobe cognitive decline, and balance issues. The clinical examination findings are diverse and PSP cases are often under-diagnosed or misdiagnosed. We report a case of a 54- year-old male patient that presented primarily with recurrent falls due to postural instability and bilateral leg weakness that had progressively worsened to being wheelchair-bound. An extensive physical examination revealed classical findings indicative of PSP.