Macroangiopathy in Systemic Sclerosis-Case Report and Literature Review

Author(s): Topolyanskaya SV, Bubman LI

The case report of systemic sclerosis debuting in an elderly man with critical ischemia of the lower extremities and with amputation of both legs is described. The features of this case included the large vessels pathology in the very beginning of the disease, as well as the occurrence and rapid progression of significant fibrosis and hyperpigmentation of the lower limbs skin after amputation of one of them. At the same time, the Raynaud phenomenon, sclerodactyly, and signs of visceral pathology were absent in the patient. Possible causes of the development of macroangiopathy in patients with systemic sclerosis are discussed.



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