Comparison of Computed Tomographic Hounsfield Numbers with Ultrasonographic Categorization of the Fatty Liver Disease

Author(s): Muhammad Yousaf, Dr. Sarah Maryam, Dr. Muhammad Fiaz, Dr. Asif Hanif, Mehreen Fatima, Dr. Raham Bacha, Syed Muhammad Yousaf Farooq, Syeda Rabi Madina, Professor Dr. Syed Amir Gilani

Objective: To compare CT Hounsfield Numbers with Ultrasonographic categorization of the FLD.

Material and Methods: It was a Cross sectional analytical study. By Purposive sampling 227 Patients of FLD were sampled from Radiology Department AL Razi Healthcare MM Alam Road Lahore and Radiology Department Shalamar Hospital Shalamar Road Lahore. The data was collected for 9 months. Patients of both gender of age between 20-80 years, who underwent both CT and USG scans of abdomen and with Ultrasonographic diagnosis of diffuse FLD was included. The USG categories of FLD were compared with mean Liver CTHFN. Statistical analysis was done by ANOVA; p value of CTHFN was found significant for each Ultrasonographic category of FLD.

Results: In this study 227 patients of FLD was taken. The mean age of population was 49.88 ± 14.52 years. The frequency of male population was 141(62.11%) and female was 86 (37.89%). The mild, moderate and severe FLD was found in 159 (70.04%), 50(22.03%) and 18(7.93%) patients respectively. The mean values of Liver CTHFN in mild, moderate and sever FLD categories by USG were 42.08 ± 5.07 HU, 24.41 ± 4.19 HU and 3.09 ± 6.64 HU respectively. These values along with P values and 95% Confidence Interval (CI). In multiple comparison the Least Significant Difference (LSD) of USG categories of FLD with mean Liver CTHFN, p value was significant when mild FLD was compared with moderate and severe FLD, Moderate FLD was compared with mild and severe FLD and severe FLD was compared with mild and moderate FLD.

Conclusion: In best of our knowledge to date this is third study comparing USG grades of FLD with CTHFN to determine CTHFN for each Ultrasonographic category of FLD. We found significant p values of CTHFN for all grades of FLD by USG. CTHFN decreased with severity of FLD. Hence we can conclude that USG is a reliable and sensitive modality for the grading of FLD.

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