A Comparative Study on Efficacy of Azithromycin and Minocycline in the Treatment of Acne Vulgaris

Author(s): Farzana Afroz, Rashidul Hasan, Rajib Shahriar

Background: Acne is a chronic inflammatory condition of the pilosebaceous units that is also a multifactorial skin lesion. Dermatologists treat acne vulgaris, one of the most prevalent skin conditions, which primarily affects teens but can occur at any age.

Objective: The aim of the study to compare the efficacy of azithromycin and minocycline in the treatment of acne vulgaris.

Methodology: This cross-sectional study was conducted at tertiary care hospital Dhaka District from June 2021 to July 2022. A total of 120 patients diagnosed with acne regardless of age and sex. Data collection was done after approval of protocol using a semi-structured questionnaire through face-to-face interview. Data were analyzed using a computer program SPSS 25.0 version. Result: The mean (±SD) of the patients. The mean (±SD) age of the total sample was 27.26(±4.97). In Azithromycin group it was 25.97(±3.86), In Minocycline group 23.87(±7.84). The minimum age of the total sample was 16 years, maximum age was 45. Among all the patients 65% were female. The reduction in the percentage, in the number of inflammatory lesions, non-inflammatory and total lesions of post six weeks was better with azithromycin group as compared to minocycline.

Conclusion: Patients with acne who received azithromycin and minocycline separately in the current study, showed improvements in a number of criteria measuring the severity of the lesion.