Costs associated with Female Urinary Incontinence: an integrative review of the literature

Article Information

Julieta Aránguiz-Ramíreza,b,*, Pedro Olivares-Tiradoc, Xavier Castells-Oliveresd

a Doctoral Program in Biomedical Research Methodology and Public Health at the Department of Pediatrics, Obstetrics and Gynaecology, Preventive Medicine and Public Health at the Autonomous University of Barcelona (UAB), Barcelona, Spain

b Assistant teacher. Department of Obstetrics and Neonatology of Diego Portales University, Santiago, Chile

c Public Health Program, School of Public Health, Faculty of Medicine, University of Chile, Santiago, Chile

d Department of Epidemiology and Evaluation, IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain. Autonomous University of Barcelona, Spain

*Corresponding Author: Julieta Aránguiz-Ramírez, Doctoral Program in Biomedical Research Methodology and Public Health at the Department of Pediatrics, Obstetrics and Gynaecology, Preventive Medicine and Public Health at the Autonomous University of Barcelona (UAB), Barcelona, Spain.

Received: 20 December 2022; Accepted: 27 December 2022; Published: 30 December 2022

Citation: Julieta Aránguiz-Ramírez, Pedro Olivares-Tirado, Xavier Castells-Oliveres. Costs associated with Female Urinary Incontinence: an integrative review of the literature. Obstetrics and Gynecology Research 5 (2022): 325-333.

View / Download Pdf Share at Facebook


In women, the anatomical peculiarities of the pelvic floor and the risk factors for its dysfunction predispose women to suffer from Urinary Incontinence (UI), a condition that, although it does not pose a vital risk, negatively affects their quality of life and represents a high risk of the economic cost, still invisible.


To describe the scientific evidence available regarding studies of costs associated with UI in women.


Integrative review of the literature using the PubMed, Embase, ScienceDirect and Scopus databases as data sources, on studies of direct and indirect costs of UI. in women, published between 2009 and 2022. Using the search terms in Spanish and/or English: “Cost of illness”, “direct cost”, “indirect cost”, “urinary incontinence” and “woman”. The monetary values were adjusted from the date of the study to December 31,2021 and local currencies were converted to USD.


Of the 302 articles reviewed, 14 met the criteria for analysis. Some studies considered the estimate of the total economic burden including direct and indirect costs. The annual direct cost per capita ranges from US$ 153.71 to US$ 32,709 depending on the country, medication use and age, the indirect cost corresponds to an average 160 hours per year for presenteeism.


In high-income countries, the economic burden for urinary incontinence is notorious, in Latin American and Caribbean countries there are no economic evaluations regarding it, to improve the benefits for women's health, it is advisable to update.


Cost of Illness; Direct Cost; Indirect Cost; Urinary Incontinence; Woman

Cost of Illness articles Cost of Illness Research articles Cost of Illness review articles Cost of Illness PubMed articles Cost of Illness PubMed Central articles Cost of Illness 2023 articles Cost of Illness 2024 articles Cost of Illness Scopus articles Cost of Illness impact factor journals Cost of Illness Scopus journals Cost of Illness PubMed journals Cost of Illness medical journals Cost of Illness free journals Cost of Illness best journals Cost of Illness top journals Cost of Illness free medical journals Cost of Illness famous journals Cost of Illness Google Scholar indexed journals Direct Cost articles Direct Cost Research articles Direct Cost review articles Direct Cost PubMed articles Direct Cost PubMed Central articles Direct Cost 2023 articles Direct Cost 2024 articles Direct Cost Scopus articles Direct Cost impact factor journals Direct Cost Scopus journals Direct Cost PubMed journals Direct Cost medical journals Direct Cost free journals Direct Cost best journals Direct Cost top journals Direct Cost free medical journals Direct Cost famous journals Direct Cost Google Scholar indexed journals Indirect Cost articles Indirect Cost Research articles Indirect Cost review articles Indirect Cost PubMed articles Indirect Cost PubMed Central articles Indirect Cost 2023 articles Indirect Cost 2024 articles Indirect Cost Scopus articles Indirect Cost impact factor journals Indirect Cost Scopus journals Indirect Cost PubMed journals Indirect Cost medical journals Indirect Cost free journals Indirect Cost best journals Indirect Cost top journals Indirect Cost free medical journals Indirect Cost famous journals Indirect Cost Google Scholar indexed journals Urinary Incontinence articles Urinary Incontinence Research articles Urinary Incontinence review articles Urinary Incontinence PubMed articles Urinary Incontinence PubMed Central articles Urinary Incontinence 2023 articles Urinary Incontinence 2024 articles Urinary Incontinence Scopus articles Urinary Incontinence impact factor journals Urinary Incontinence Scopus journals Urinary Incontinence PubMed journals Urinary Incontinence medical journals Urinary Incontinence free journals Urinary Incontinence best journals Urinary Incontinence top journals Urinary Incontinence free medical journals Urinary Incontinence famous journals Urinary Incontinence Google Scholar indexed journals Woman articles Woman Research articles Woman review articles Woman PubMed articles Woman PubMed Central articles Woman 2023 articles Woman 2024 articles Woman Scopus articles Woman impact factor journals Woman Scopus journals Woman PubMed journals Woman medical journals Woman free journals Woman best journals Woman top journals Woman free medical journals Woman famous journals Woman Google Scholar indexed journals Overactive bladder articles Overactive bladder Research articles Overactive bladder review articles Overactive bladder PubMed articles Overactive bladder PubMed Central articles Overactive bladder 2023 articles Overactive bladder 2024 articles Overactive bladder Scopus articles Overactive bladder impact factor journals Overactive bladder Scopus journals Overactive bladder PubMed journals Overactive bladder medical journals Overactive bladder free journals Overactive bladder best journals Overactive bladder top journals Overactive bladder free medical journals Overactive bladder famous journals Overactive bladder Google Scholar indexed journals Quality of life articles Quality of life Research articles Quality of life review articles Quality of life PubMed articles Quality of life PubMed Central articles Quality of life 2023 articles Quality of life 2024 articles Quality of life Scopus articles Quality of life impact factor journals Quality of life Scopus journals Quality of life PubMed journals Quality of life medical journals Quality of life free journals Quality of life best journals Quality of life top journals Quality of life free medical journals Quality of life famous journals Quality of life Google Scholar indexed journals human resources articles human resources Research articles human resources review articles human resources PubMed articles human resources PubMed Central articles human resources 2023 articles human resources 2024 articles human resources Scopus articles human resources impact factor journals human resources Scopus journals human resources PubMed journals human resources medical journals human resources free journals human resources best journals human resources top journals human resources free medical journals human resources famous journals human resources Google Scholar indexed journals material resources articles material resources Research articles material resources review articles material resources PubMed articles material resources PubMed Central articles material resources 2023 articles material resources 2024 articles material resources Scopus articles material resources impact factor journals material resources Scopus journals material resources PubMed journals material resources medical journals material resources free journals material resources best journals material resources top journals material resources free medical journals material resources famous journals material resources Google Scholar indexed journals administrative management articles administrative management Research articles administrative management review articles administrative management PubMed articles administrative management PubMed Central articles administrative management 2023 articles administrative management 2024 articles administrative management Scopus articles administrative management impact factor journals administrative management Scopus journals administrative management PubMed journals administrative management medical journals administrative management free journals administrative management best journals administrative management top journals administrative management free medical journals administrative management famous journals administrative management Google Scholar indexed journals

Article Details


UI: Urinary incontinence; OAB: Overactive bladder; DC:  Direct Cost; IC: Indirect Cost; Qol: Quality of life

U.S: United States; LAC: Latin America and the Caribbean; PC : Per capita


To achieve necessary conditions in health and well-being in the population, it is necessary to implement public policies that address the determinants of health, ensuring universal access and coverage. [1] For this, it is indispensable in health management and resource allocation, health economics, which provides information for the orientation of decision-making in pathologies of high prevalence, mortality or social loss. [2]

Urinary incontinence (UI), although it has no lethality, due to the anatomical particularities of the pelvic floor and the risk factors for its dysfunction, make it one of the most frequent pathologies in women, with an international prevalence of 29% to 75% depending on age [3,4]. UI also generates a significant deterioration in quality of life (QoL), having an impact on emotional well-being, a higher rate of severe depression and anxiety, alternating relationship activities with others, loss of self-esteem, social isolation and a series of associated comorbidities [5,6,7].

Given the multidimensional effect of the clinical situation, it also implies an economic impact for both the individual and society. However, there are very few data available that make this economic burden visible, mostly consider the direct cost (DC) for the treatment of UI and to a lesser extent include comfort and care to cope with it, estimating that in developed countries it is at least 2% of the health budget [8]. In a smaller number of studies, the implications for loss of productivity or indirect cost (IC) are considered difficult to determine due to the variables to be considered [8].

Milson & Coyne (2014), in a systematic review on global prevalence and economic costs, reports that in multinational studies the annual estimates of disease cost for UI were €2.9 billion for DC in five European countries in 2000 and €7 billion for the sum of DC and IC for Canada and five European countries in 2005, and mentions that the cost of the disease to the U.S. in 2007 was $66 billion USD [9].

To carry out an economic impact assessment of diseases, the method used is the "Cost of illness", whose objective is to identify and measure the costs of a particular disease, including as far as possible, DC, IC and intangible costs; expressed in monetary terms from a societal perspective [10,11]. The Cost of illness scope can range from the incidence or prevalence of the disease to its effect on longevity, morbidity, decline in QoL, and financial aspects, including DC and IC arising from comorbidity, complications, disability, or premature death [12].

In the field of health economics, the concepts of cost and expense are different from those used in financial accounting. Costs are not only measured by income, but also by benefits, well-being and QoL. On the other hand, expenditure is a category in which the health institution incurs, considering human and material resources, these being increased by the epidemiological and demographic changes of the population, technology, the price of medicines, training and research needs, as well as the administrative management of the unit [13].

The objective of this study is to contribute with evidence regarding the costs associated with UI in women under 64 years of age, making visible the economic burden and establishing one to carry out local economic evaluations.


An integrative review was selected as a search method because this approach allows to examine the emerging evidence when it is not yet clear what other more specific questions can be raised and addressed through a more precise systematic review, thus summarising the existing theoretical or empirical literature that allows an integral understanding of a particular phenomenon [14,15],  which in this study provides a preliminary evaluation of the available literature on costs associated with urinary incontinence in women.

The integrative review was conducted following the protocol explained by Arksey and O'Malley (2005), updated for Peters et al (2015) and Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR) [16,17].

The protocol includes five steps: (a) define research questions; (b) define eligibility criteria; (c) identify relevant studies through a search strategy; (d) data graphics, i.e., extracting, synthesizing and interpreting data; and, (e) summarise and report results [16,17].

The objective of the review was addressed by keeping in mind the following research question: What is the direct and indirect cost of UI in women aged 20 to 64 years? To answer this question, a search was made for international studies, with special interest in Latin American and Caribbean countries (LAC), on economic evaluation of health with an approach to information on direct and/or indirect costs of UI in women.

Relevant definitions associated with the problem:

The construction of the main question was done through concepts that define the problem and the components of the costs associated with it.

Urinary Incontinence: The International Continence Society (ICS) defines UI as involuntary loss of urine [3,4].

Overactive Bladder: ICS as "clinical syndrome characterised by the presence of isolated micturition urgency, or in combination with urge urinary incontinence, together with an increase in micturition frequency and nocturia in the absence of another demonstrable disease" [18].

Direct cost (DC): are those that correspond to medical care such as diagnosis, treatment and rehabilitation; non-health costs incurred by the health system, the family and the individual patient such as transportation, household expenses, comfort and informal care of any kind [12]

Indirect Cost (IC): refers to "productivity losses or productivity costs" due to morbidity and mortality, borne by the individual, family, society or employer, forming part of social welfare losses [12,13]

Search strategy

The search strategies were developed based on keywords and terms of Medical Subject Headings (MeSH) that are related to: "Cost of illness", "Direct Cost", "Indirect Cost". "Urinary Incontinence" and "Woman.  An extensive search was carried out in the electronic databases of: PUBMED, Embase, ScienceDirect, Scielo and Scopus.

Inclusion and exclusion criteria:  

Original articles were included that comprised direct and/or indirect costs whose results were expressed in monetary units, published in English and Spanish between 2009-2021 and that included women with urinary incontinence between 20 and 64 years old in their sample.

Studies conducted only with elderly people, only in patients with associated neurological pathologies, opinion articles, interviews and proceedings of conferences or congresses, systematic reviews, meta-analyses and theses were excluded.

Selection of studies

The review was conducted by two investigators (lead author and co-author) and guided by the PRISMA-ScR statement. All kinds of documents were included. The titles and abstracts of the documents identified through the database were downloaded to an Excel spreadsheet and then both researchers independently reviewed them based on eligibility criteria and their relevance to the research question.  Subsequently, for the final selection of the documents, the full texts of the selected articles were downloaded, which were independently reviewed by the researchers according to the eligibility criteria. Disagreements over article selection or function domains were resolved by discussion between the two authors until consensus was reached.

Data Analysis:

The analysis of the information was carried out by critically reading the qualitative and quantitative content of the selected articles. The description of the articles was carried out applying thematic categories for the construction of the summary tables, the first being the identification of the methodology, the second the origin of obtaining the direct and indirect costs of each study and the last is the cost referred by each author in local currency and USD (US dollar).

For the critical analysis of the costs considered in each study, the currency was adjusted for inflation from the year the study was published to December 31, 2021 according to the World Bank, described in results. This date is considered cut-off due to the Covid-19 pandemic and its subsequent impact on the world economy. In addition, the local currency of the study was converted to USD (US dollars) of the same date to unify the information.


For the selection of the articles, the references reported in each of the search engines were used according to the inclusion and exclusion criteria established in this study. The search with the keywords resulted in 302 studies published between 2009 and 2015, without presenting national or international updates later.

After reading the abstracts and according to the inclusion criteria, 22 of the articles complied with the request, however, in the critical analysis of the full texts, 8 articles were rejected, leaving 14 for the study. The search flowchart is shown in (Figure 1).


Figure 1:Search Strategy Flowchart

The methodological, objective and sample characteristics of the studies are heterogeneous, however, the methodological approach used was for all quantitative articles (Table N°1)

Table icon

Table 1: Methodological characteristics of the articles included in the integrative review

One of the most important concepts for critical analysis are the considerations of direct costs (DC) and indirect costs (IC) that each of the authors incorporated into their studies (Table N°2).

Table icon

Table 2: Characteristics of the data collection of Direct and Indirect Costs

To determine the IC, the authors considered absenteeism (absence from work due to health problems), presenteeism (employees go to work, but dedicate part of the working day to tasks that are not productive or are not related to the company, either for health reasons, lack of motivation, personal problems or mental block) and QoL.

Regarding the DC reported in the studies, it is observed that health costs such as medical visits, supplies and medicines were considered; and as non-sanitary costs comfort, laundry, use of sanitary towels (pads for incontinence).

The values extracted from the IC, DC and Total Cost (IC+DC) were adjusted according to inflation from the year of publication to December 31, 2021 and are presented in (table 3), it is also highlighted that the values were converted to their equivalent in USD of the same date. It is worth mentioning that the study by Lee KS & Choo MS was not considered as it did not contain analysis of cost data.

Table icon

Table 3: Results of direct and indirect costs updated according to inflation from January of the year of publication to December 31, 2021 and local currency converted to USD


Urinary Incontinence is a clinical situation that generates a significant cost both for the population that is affected, as well as for health systems and society [33]. In addition, the well-known repercussions on women's QoL in the mental and physical areas [5] in turn cause a decrease in work productivity and daily household chores, a situation that would be compensated in the case of users who receive adequate and timely treatment [26,31].

Sexton & Coyne in their study of the level of productivity in people with UI, report that in women with minimal symptoms of UI decreases to 72% the chances of working full time, in the case of those with OAB to 75% and 67% if they had both. In addition, 36% of women reported having to always be worried about frequently interrupting meetings due to this situation[23].

The Kannan & Radican (2009) study in the US demonstrated, when followed for 7 days in workers with lower urinary tract symptoms, an absenteeism rate of 4.01%, a 9.08% of presenteeism and an 8.03% loss of labour productivity combined by both due to this situation, that is, an equivalent of 3.2 hours within a 40-hour workweek which leads to a loss Total 160 hours or 4 weeks of annual productivity [30].

On the other hand, Brodszky & Gulácsi (2012)  mention in their study that applying the questionnaire for the deterioration of activity and labour productivity (WPAI) in active workers resulted in absenteeism of 0.4%, presenteeism of 44.6% and impaired activity of 48.2%, the latter was 50.7% for non-workers.[32].

Goren & Zou (2014) report that annual costs in US per person using drug for UI compared to those who do not use it was US$ 32,709  against US$ 25,759  for direct costs, due to the greater number of medical visits for the former, and US$ 10,525 versus US$ 11,547 respectively for indirect costs, data obtained by the National Health Survey of 2011 in the US applied to 75,000 people [31].

Sung & Washington (2010) only calculated for their DC study, they report an average annual cost only for women aged 21-44 years of US$ 54.45 million [27], an age group in which this condition is even more invisible.

In addition, two studies project the costs obtained, reported values that were adjusted for the corresponding inflation of the study year towards December 31, 2021, where Ganz & Smalarz (2010)  report a total annual national cost of US$ 82.24 billion, and based on an economic model of prevalence NOBLE (National Overactive Bladder Evaluation) projected for the past 2020 an increase of 25% since 2007 in the annual cost per UI for the US, which would be equivalent to US$ 106.92 billion adjusted [20].  On the other hand, Cahil & Donhardt (2010) mention a total annual financing per capita cost for UI of US$ 8766, projecting that by 2030, Australia would have a national cost of US$ 59.9 billion[19].

Therefore, within the strengths of the study, despite the scarce number of existing articles on direct and indirect costs of the UI, the selected ones give us evidence that demonstrates the invisible economic impact on women living with UI, allowing to lay the foundations for a reflection on the economic burden that involves silent pathology, but of high prevalence. The relevance of this study for public health is to make visible the costs associated with neglected UI in women, especially in young adults, due among other things, to the fact that most of the studies focus on older adults.

Another data that could be extracted from the articles was the prevalence of UI reported in the study of Cahil & Donhardt for Australia, where they consider in 2010 an N = 4.2 million people with UI over 20 years (21% of the population) and a projection for 2030 of a N = 5.6 million people affected [19], which suggests that with the way of life in similar countries it would be expected that this clinical situation begins to increase its prevalence.

Among the limitations of the review is that the studies on UI carried out in Chile and LAC are from a theoretical-practical approach, considering pathophysiology, treatment and rehabilitation of the pelvic floor, but do not perform analysis of health costs or loss of productivity, so it could not include local or regional studies. Another limitation was the heterogeneity of the methodological designs and the dissimilar characteristics of the studies, as well as the lack of updating at the international level in economic evaluations on this topic.

It is worth mentioning that the programs implemented in Chile and LAC for UI, consider the health DC of the UI treatments determined by the health insurance or health insurance they have, without considering the loss in productivity and/or QoL. In Chile, close to 100% of the population is covered by some health insurance, of the total 80% being covered by public health insurance or FONASA. For example, for reparatory surgery by UI the co-payment by the FONASA beneficiaries in the public hospital network can until  US$60  on the other hand, given that the waiting list for non-priority treatment is long, since 2022 a package was incorporated for surgical treatment of the nocturia of effort with a co-payment by the beneficiary close to US$1,000 and can be attended in an institution in agreement [33,34]. As for the population with the highest economic income belonging to the private health insurance (ISAPRE), the values that the beneficiary must pay will depend on the coverage of the contracted plan and the use or not of the institution of preference according to the ISAPRE to which the person belongs, ranging from US$ 300 to US$600 for reparatory surgery. Despite the above, difficulties persist for women to access care that determines more complex health-disease processes, also considering that in Chile the overall burden of disease in women is greater than in men [35].

Epidemiological and demographic changes, modern lifestyle, environmental risk factors and emergency and disaster situations, make public policies must be dynamic and updated according to local reality. In this case, it is necessary to consider the UI as a clinical situation that must be evaluated both in the repercussions on QoL and the costs involved, training and updating primary care professionals for prevention and early detection. On the other hand, worldwide cost studies are not updated or mostly do not consider women under 50 years of age in this problem.


In conclusion, in recent years health economics has been a key area in decision-making in public policies, since, with their studies, health services support the development of strategies to deal with critical situations by considering the costs involved in the different alternatives.  Regarding UI, the studies analysed demonstrated high direct costs, both health and non-health and indirect costs translated into a decrease in labour productivity that leads to the subsequent economic loss for society. It is recommended to carry out new economic and prevalence evaluation studies on this subject, to provide updated information to decision makers.


J Aránguiz-Ramírez: Selection of studies, Manuscript writing.

P Olivares-Tirado: Selection of studies, Thesis Director

X Castells-Oliveres: Reviewer, Thesis Co-director


All authors declare that they have no conflicts of interest.


Self-financed, corresponding to completion of the doctoral program.


  1. PAHO. Monitoring Framework for Universal Health in the Americas. Washington, D.C.: Pan American Health Organization; 2021: Chapter 1. ISBN 978-92-75-12270-9.
  2. Collazo M., Cárdenas J., González R., et al. Health economics Should it be of interest to the health field? Pan American Journal of Public Health. (2022): 359-365.
  3. Rincon O.(2015); Clinical characterization of UI and associated factors in users of the Women's Unit of the " Ultraestación " Family Health Center in the city of Chillán, Chile. Chilean Medical Journal. 143; 203-212.
  4. Botros C, Prevalence of urinary incontinence symptoms: looking beyond stress & urgency urinary incontinence. IUGA Academy. 2017, Vol 23.
  5. Aránguiz J, Olivares P, Sandaña, C. et al., Health-related quality of life in women aged 20-64 years with urinary Incontinence . International Urogynecology journal (2022) Sept 27: 1-10
  6. Goforth J, Langaker _ M. ; Urinary Incontinence in Women; NC Med J. (2016) Nov-; 77(6): 423-425.
  7. Ghezzi F, Serati M; The epidemiology of urinary incontinence: a case still open, Ann Translational Med. (2016); 4(6): 123.
  8. C González-Ruiz de León, M L Pérez-Haro A. Jalón-Monzón, J. García-Rodríguez. Update on female urinary incontinence. Semergen Family Medicine. (2017), Vol. 43(8): 578-584.
  9. Milsom I, Coyne K S, Nicholson S, et al., Global Prevalence and Economic Burden of Urgency Urinary Incontinence: A Systematic Review; European Urology (2014); Vol 65: 79-95
  10. Soto Alvarez Javier. Chapter III Types of costs to include in an economic evaluation. In: Economic evaluation of medicines and health technologies: Principles, methods and applications in health policy. 2nd ed. Madrid; (2012): 37-40.
  11. Phillips V, Tehran AB, Langmuir H. et al., Treating Urge Incontinence in Older Women: A Cost-Effective Investment in Quality-Adjusted Life-Years (QALY), Journal of Geriatrics (2015); 2;1-7
  12. Byford S, Torgerson D, Rafiery J. Economic Note. Cost Of Illness Studies. BMJ (2000). Vol 320.
  13. Changik Jo, Cost-of-illness studies: Concepts, scopes, and methods, Clinical Molecular Hepatology (2014); 327-337.
  14. Whittemore R, Knafl K. The integrative review: updated methodology. J Adv Nurs 2005; 52(5): 546-553
  15. Guirao Goris S J A; Utility and types of literature review . Santa Cruz de La Palma (2015) Vol.9(2).
  16. Arksey H, O'Malley L. Scoping Studies: Towards a Methodological Framework.” InternationalJournal _ of Social Research Methodology: Theory and Practice (2005): 8(1): 19-32.
  17. Peters M, Godfrey C, Khalil H, et al. Guidance for driving Systematic Scoping reviews . International Journalvof Evidence-Based Healthcare (2015) 13(3): 141-146.
  18. Angulo J C, Calderín M P, Fernández Y, et al., Prevalence and characterization of overactive bladder detected in a population of Madrid with the self-administered OAB-V3 questionnaire in primary care. Atten Elementary. (2018); 50(2): 79-87.
  19. Cahil B, Donhardt D, Tucker I, et al., Continence Foundation of Australia; The economic impact of incontinence in Australia, Doloitte Access Economics (2011).
  20. Ganz M L, Smalarz A M, Krupski T L, et al., Economic costs of overactive bladder in the United States. Urology. (2010); 75(3): 526-532.
  21. Onukwugha E., Zuckerman I H, McNally D, et al., The Total Economic Burden of Overactive Bladder in the United States: A Disease-Specific Approach; Am J Manag Care. (2009); vol 15: 90-97.
  22. Subak L L, Marinilli Pinto A, Wing R R et al., Decrease in Urinary Incontinence Management Costs in Women Enrolled in a Clinical Trial of Weight Loss to Treat Urinary Incontinence; Obstet Gynecol. (2012); 120(2 Pt 1): 277–283.
  23. Sexton Ch C, Coyne K S, Vats V, et al., Impact of Overactive Bladder on Work Productivity in the United States: Results from EpiLUTS ; Am J Manag Care. (2009); 15: 98-107.
  24. Tang Derek H, Colayco Danielle C, Khalaf Kristin M, et al., Impact of urinary incontinence on healthcare resource utilization, health-related quality of life and productivity in patients with overactive bladder; BJU Int (2014); 113: 484-491.
  25. Lee K S, Choo M S, Seo J T, Oh SJ et al. Impact of overactive bladder on quality of life and resource use: results from the Korean Burden of Incontinence Study (KOBIS). Health Qual Life Outcomes,(2015); 13: 89.
  26. Subak L, Goode P, Brubaker L, et al., Incontinence Management Costs are Reduced Following Burch or Sling Surgery for Stress Incontinence, and for the Urinary Incontinence Treatment Network; Am J Obstet Gynecol. (2014); 211(2): 171.e1–171.e7.
  27. Sung V, Washington B and Raker C h; Costs of ambulatory care related to female pelvic floor disorders in the United States; Am J Obstet Gynecol. Am J Obstet Gynecol . (2010) ; 202(5): 483.e1–483.e4.
  28. Sung W, You H, Yoon T Y ; Socioeconomic Costs of Overactive Bladder and Stress Urinary Incontinence in Korea; Korea International Neurology Journal (2012); 16:23-29.
  29. Sicras-Mainar A, Ruiz- Torrejo A, Navarro-Artieda R. et al., Impact of Loss of Work Productivity in Patients with Overactive Bladder Treated with Antimuscarinics in Spain: Study in Routine Clinical Practice Conditions; Springer International Publishing Switzerland, (2015) 35(12): 795-805.
  30. Kannan H, Radican L, Turpin R S, et al., Ambulatory and Office Urology Burden of Illness associated with lower Urinary Tract Symptoms: Including Overactive Bladder/Urinary Incontinence; Ambulatory and Office Urology (2009); 74: 34-40.
  31. Goren A, Zou K H, Gupta S K et al., Direct and indirect cost of urgency urinary incontinence with and without pharmacotherapy. Int J Clin Pract. (2014) ; 68(3): 336-348.
  32. Brodszky V, Gulácsi L, Majoros A, Péntek M, et al; Cost of Illness of Overactive Bladder Syndrome in Hungary; Value in Health. 2012, vol 15(7): A456
  33. Aguilera X, Castillo C, Covarrubias T, Delgado-Becerra I, Fuentes-Bravo R et al., Structure and functioning of the Chilean health system; Center for Epidemiology of Health Policies, Universidad del Desarrollo, (2019).
  34. FONASA, PAD bonus (2022)
  35. Paredes-Fernández D, Lenz-Alcayaga R, Rojas-Cáceres C, Carroza Escobar M. Women's access to health care: gaps that the future health reform in Chile must solve. Medwave (2021); 21(10)

© 2016-2024, Copyrights Fortune Journals. All Rights Reserved