Pregnancy Complicated by Hyperinsulinemic, Non-Insulinoma Hypoglycemia Syndrome: Case Report

Author(s): Enio Luis Damaso, Conrado Sávio Ragazini, Mariane Nunes de Nadai, Patrícia Moreira Gomes, Raphael Del Roio Liberatore Junior, Elaine Christine Dantas Moisés

Hyperinsulinemic hypoglycemia is an unusual metabolic disorder characterized by frequent episodes of hypoglycemia caused by uncontrolled insulin release. In pregnancy it can result in adverse perinatal outcomes. We report a rare case of a pregnant woman diagnosed with this disorder. During the first pregnancy, drug treatment was necessary, and the second pregnancy occurred after partial pancreatectomy, which allowed good control with nutritional support. Hyperinsulinemic hypoglycemia syndrome complicating pregnancy, although very rare, should be included in the differential diagnosis of hypoglycemia during pregnancy.