Impact of Negative Air Pressure on "Mortality" in ICU Setting

Author(s): Mufti Mahtub Moontasir Bhuiyan, Tania Tofail, IRM Sazzad Haider, Md. Gisan Hossain, Mahin Muntakim, Mir Shahadat Hossain, Moshfiqur Rahman Chowdhury

Abstract This retrospective observational study aimed to investigate the impact of various factors on patient outcomes in the intensive care unit (ICU) setting, including demographic characteristics, vaccination status, antiviral treatment, and environmental factors such as negative air pressure. Data were collected from electronic medical records of patients admitted to the ICU during a specified period. Descriptive statistics and inferential analyses, including chi-square tests and Mann-Whitney U tests, were performed to assess associations between variables and patient outcomes at 28 days post-admission. Demographic analysis revealed no significant association between age group or gender and patient outcomes. Similarly, there was no statistically significant correlation between vaccination status and patient outcomes, nor between treatment with antiviral medication and 28-day outcomes. However, the presence of negative air pressure in ICU environments showed a significant association with reduced mortality rates, highlighting its importance in patient care. These findings underscore the need for further research to explore additional factors influencing patient outcomes in critical care settings. Prospective studies with larger sample sizes and longer follow-up periods are warranted to validate these findings and identify potential confounding factors. Optimization of ICU environments, including measures to ensure negative air pressure, may contribute to improved patient outcomes and reduced mortality rates. Overall, this study provides valuable insights into factors affecting patient outcomes in the ICU and informs strategies to enhance patient care and healthcare delivery in critical care settings.