Effectiveness of Topical 100% Trichloroacetic Acid in Treatment of Anogenital Warts in Male Patients

Author(s): Abdul Qayum, Mohammad Majid Paracha, Farah Sagheer

Introduction: Anogenital warts are benign proliferation of skin and mucosa that result from different types of human papilloma viruses (HPVS). Treatment of AGW is aimed at relieving the patient physical and psychological discomfort and preventing the spread of infection by autoinoculation. There is evidence that localized topical application of trichloroacetic acid (100 %) is effective against AGW but due to differences in skin types and possible differences in papilloma virus’s types, it was necessary to confirm its effectiveness in Pakistani Population.

Objectives: The objective of this study was to ascertain the effectiveness of topical 100 % Trichloroacetic acid in the treatment of anogenital warts on male external genitalia.

Methodology: This descriptive case series study involved 90 cases having AGW (5-20 lesions) on clinical examination. Written informed consent was taken from all patients. Patients were followed at the end of 6 months after completion of treatment and recurrence of AGW was noted. Results: The mean age of the patients was 29.82±7.56 years and all the patients included in study were male. 74 patients out of 90 showed complete clearance of anogenital warts at end of 6 months of treatment however 16 patients out of 90 had recurrence. Hence topical trichloroacetic acid is effective in 82.2% of studied patients. Conclusion: Topical trichloroacetic acid (100%) is an effective treatment of anogenital warts on male external genitalia with complete cure in 82.2% patients at the end of 6 months of treatment.

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