A Severe Hyperbilirubenmia in Gilbert Syndrome

Author(s): Batoul Sadek, DO, Mohamed Hashem, DO, Fisnik Cake, DO

Bilirubin is a waste product produced by the breakdown of red blood cells. Gilbert Syndrome is a genetic disorder that affects the liver's ability to process bilirubin (1). Gilbert syndrome consists of periodic episodes of mild jaundice, which can cause symptoms such as fatigue, abdominal pain, and dark urine (2). Gilbert syndrome is often misdiagnosed for a more serious liver disorder, however, it is a benign syndrome. Most cases of Gilbert syndrome consist of hyperbilirubinemia. Typically bilirubin levels in Gilbert Syndrome is less than three, with rare instances of it being above 3; however, it typically does not surpass 6 mg/dL. This case study describes a unique clinical presentation of a patient with Gilbert syndrome. This case is unique because the patient consistently has hyperbilirubinemia and it is at levels above 20 mg/ dL. Additionally this case is unique in that the patient did not have any abdominal pain or signs of hepatic disease. Given the unique presentation of this disease, it is important to share our approach with others.

© 2016-2025, Copyrights Fortune Journals. All Rights Reserved