A Case of Cytomegalovirus Corneal Endotheliitis in a Juvenile Male with a History of Repeated Intraocular Hypertension

Author(s): Hisataka Fujimoto, Junichi Kiryu

Purpose: Here we report a case of cytomegalovirus corneal endotheliitis in the right eye of a young boy with a history of repeated intraocular hypertension.

Observations: The patient’s right eye had a history of four episodes of cytomegalovirus corneal endotheliitis with the intraocular hypertension. His ages at these occurrences were 9.91, 10.03, 12.12, and 12.67 years. In each event, keratic precipitates including coin-shaped lesions, the cytomegalovirus characteristic types of keratic precipitates, focal corneal stromal edema coincidence with coin-shaped lesions were observed and diagnosed as cytomegalovirus corneal endotheliitis with trabecular meshwork inflammation that caused the intraocular hypertension. In each event, topical ophthalmic solutions including 0.1% betamethasone 5 times a day and 0.4% ripasudil twice a day led to remission within 7 days. At the last cytomegalovirus corneal endotheliitis recurrence, cytomegalovirus was detected in the aqueous humor by qualitative polymerase chain reaction at the concentration of 1.78×104 copies/mL

Conclusion and Importance: In this case, cytomegalovirus corneal endotheliitis occurred at 9 years of age. To the best of our knowledge, this patient is the youngest reported worldwide.