Cytomegalovirus Infection (CMV) and Human Immunodeficiency Virus: Diagnostic and Therapeutic Challenges in Virology

Author(s): Jorge Aponte, Juan David Vera, Aldair Chaar, Daniel Martin, Forero Yency

Human immunodeficiency virus and co-infection by cytomegalovirus (CMV) is a life threatening association with increased risk of complications and high impact in morbidity and mortality due to immunosenescence, disproportionate inflammatory response and increased viral replication of HIV if not treatment is started [1]. Multisystemic compromise can even produce retinal, gastrointestinal, hematological, pulmonary and central nervous compromise by CMV. The purpose of this review is to provide a diagnostic and therapeutic approach based on current literature and pharmacotherapeutics.